Endocrine Abstracts

Introduction: Fahr syndrome is a rare entity characterized by the presence of bilateral intracranial calcifications with predilection for the basal ganglia and dentate nuclei. It is commonly associated with endocrine disorders, particularly parathyroid and Vitamin D disturbances. Herein we report a case of pseudohypoparathyroidism revealed by Fahr syndrome.Observation: A 29-old-year male was referred to our department for symptomatic hypocalcemia. He sho...

Introduction: Diabetic foot disease is a major health problem. The identification of its risk factors should guide preventive measures. The aim of this study was to determine the factors associated with diabetic foot complications.Patients and methods: It is a retrospective study including 47 patients admitted at the department of Endocrinology in La Rabta hospital for diabetic foot complications during the years 2015 and 2016. Clinical and para-clinical...

Introduction: Although the association between parathyroid and thyroid diseases is not uncommon, the coexisting of parathyroid adenoma causing primary hyperparathyroidism (PHPT) and papillary thyroid carcinoma (PTC) is rare. Probably this can be partially explained by different embryologic origin of thyroid and parathyroid cells. Herein, we report a case of PHPT associated with synchronous bifocal PTC.Observation: A 65-year-old woman was referred to our ...

Introduction: The involvement of the thyroid gland by tuberculosis is extremely uncommon even in countries in which tuberculosis is endemic. In the majority of the reported cases, thyroid function was preserved. Herein we report a case of thyroid tuberculosis in a patient with a primary hypothyroidism.Case report: A 52-year-old woman was referred to our department for a gradually growing goiter without compressive symptoms. She presented with a productiv...

Introduction: Abnormalities in the development and migration of the thyroid gland are known to produce ectopic thyroid tissue, usually in the midline between the tongue base and the diaphragm. Hashimoto’s thyroiditis involving ectopic thyroid tissue is particularly unusual. Herein we report a case of Hashimoto’s thyroiditis developing in a midline thyroid cervical mass.Observation: A 55-year-old man was referred for hypothyroidism. His physical...

Background: Cardiothyreosis (CT) or thyrotoxic heart is associated with higher morbidity and mortality than the other forms of hyperthyroidism. Its risk factors have been investigated in a limited number of studies. The aim of our study was to identify risk factors of CT in patients with hyperthyroidism.Methods: We identified 538 patients with a hospital discharge diagnosis of hyperthyroidism from January 2000 to December 2015. Thirty five patients were ...

Subclinical hypothyroidism (SCH) is a common disorder and indications of treatment are still being debated. The aim of our study was to describe the therapeutic and evolutionary characteristics of SCH.Methods: We undertook a longitudinal retrospective study in 110 patients with SCH biologically defined by increased serum thyroid-stimulating hormone (TSH) levels (>4 mIU/l) and normal FT4. Pregnancy, age less than 18 years, personal history of partial ...

Introduction: The syndrome of resistance to thyroid hormone is a rare inherited disorder characterized by elevated circulating thyroid hormones, failure to suppress pituitary thyroid stimulating hormone (TSH) and variable tissue target hyposensitivity to thyroid hormone action. We reported the case of a RTH syndrome with a novel mutation.Case report: A 15-year-old girl was investigated for visual hallucinations and behavior disorders. Her medical history...

Introduction: Atrial fibrillation (AF) occurs in up to 15% of patients with hyperthyroidism. Although hyperthyroidism is usually regarded as a reversible cause of AF, spontaneous sinus conversion occurs in only 2/3 of patients upon the normalization of T4 levels. The aim of this study was to identify factors associated with persistent atrial fibrillation after restoration of euthyroid state.Methods: We conducted a retrospective study of 13 years. Twenty ...

Introduction: Hypopituitarism is a known cause of bone mineral loss. Our study aimed to evaluate the frequency of osteopenia and osteoporosis in patients with Sheehan’s syndrome and to evaluate its management.Subjects and methods: It is a retrospective longitudinal study concerning 60 cases of Sheehan’s syndrome that have had a bone mineral density measurement. The parameters of osteodensitometry, the received treatment and the follow up data w...